• One of the hallmarks of modern genomic research is the generation of enormous amounts of raw sequence data.As the volume of genomic data grows, sophisticated computational methodologies are required to manage the data deluge.Thus, the very first challenge in the genomics era is to store and handle the staggering volume of information through the establishment and use of computer databases.A biological database is a large, organized body of persistent data, usually associated with computerized software designed to update, query, and retrieve components of the data stored within the system. A simple database might be a single file containing many records, each of which includes the same set of information. The chief objective of the development of a database is to organize data in a set of structured records to enable easy retrieval of information.